Nikon's A1 MP is a unique multiphoton imaging system featuring a high resolution galvanometer scanner. New 4 channel non-descanned detectors with higher sensitivity, reduced dark current and broad spectral range allow for real time unmixing of closely spaced probes for accurate and high-contrast spectral imaging. This is especially important in multiphoton microscopy because of the overlap of emission spectra of probes and autofluorescence, which is often unavoidable when using a single laser line.
- Deep imaging with high-sensitivity non-descanned detector
- High precision unmixing
- Multiphoton laser beam alignment with a single click
- Sharper, brighter imaging with new high NA objectives
September 2011 - Nikon has released a new version of the Nikon A1MP systems renamed the A1MP Plus and A1RMP Plus. There are improvements in the galvo speed from 4fps to 10fps. Of course the A1R (resonant scanner) is also capable of up to 420fps (512 x 32) and can be used simultaneously with the galvo scanner for applications like FRAP and photoactivation.
High sensitivity GaAsP detectors for the Epi NDD's is now an option for well suited deep imaging. Incredible 1,300 micron depth imaging has been achieved on in-vivo samples.
Nikon has released a new model upright microscope suitable for the A1MP Plus series called the Ni-E and Dia NDD's can be added to this fixed stage microscope. A 450 micron objective is also now available for the fixed stage microscopes.